ION: A Compound Building Game is a card drafting game where players select from a number of available Ion Cards and Noble Gas cards with the goal of creating sets of compounds and inert noble gases.

Heres how the game is played: Each player is dealt eight cards, must select one of those cards and then passes the remaining. Players must choose to either bond (pair) their selected card with another Element Card or set it alone (possibly to form an ionic bond at a later time). Throughout the game, players gain additional points for building specific compounds which are listed on the Compound Goal Cards and have available a set of Action Tiles which award them additional moves throughout the game. Players score points based upon the quantity and type of neutrally balanced compounds they construct and noble gas sets they collect. After three rounds, players add their total scores from each round, subtract points from Action Tiles used, and the player with the most points wins!